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目的观察纳洛酮联合醒脑静注射液治疗急性重度酒精中毒患者的临床效果。方法选取医院收治的急性重度酒精中毒患者80例,随机分为观察组和对照组,每组40例。对照组在常规支持治疗基础上给予纳洛酮用药治疗,观察组在对照组基础上加用醒脑静注射液联合治疗。观察治疗完毕后2组患者的临床疗效,且详细记录患者治疗后的症状消失时间与意识恢复时间。结果观察组治疗总有效率为97.50%,明显高于对照组的75.00%(P<0.01);观察组治疗后症状消失时间与意识恢复时间均明显短于对照组(P<0.01)。结论急性重度酒精中毒患者采用纳洛酮联合醒脑静注射液治疗效果显著,值得临床推广应用。
Objective To observe the clinical effect of naloxone and xingnaojing injection in the treatment of patients with acute severe alcoholism. Methods Eighty patients with acute severe alcoholism admitted in hospital were randomly divided into observation group and control group with 40 cases in each group. The control group was given naloxone on the basis of routine supportive therapy, and the observation group was treated with xingnaojing injection on the basis of the control group. After treatment, the clinical efficacy of two groups of patients was observed, and the symptom disappearance time and consciousness recovery time after treatment were recorded in detail. Results The total effective rate in observation group was 97.50%, which was significantly higher than that in control group (75.00%, P <0.01). The disappearance time and consciousness recovery time in observation group were shorter than those in control group (P <0.01). Conclusion Acute severe alcoholism patients treated with naloxone combined with xingnaojing injection has a significant therapeutic effect and is worthy of clinical application.