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目的:分析高原肺水肿(HAPE)继发急性呼吸窘迫综合征(ARDS)患者心脏标志物及心功能变化。方法:选取5年来我院收治的24例高原肺水肿继发呼吸窘迫综合征患者作为实验组,同时选取24例初进玉树地区健康志愿者作为对照。结果:24例实验组患者肌酸激本科同工酶(CK-MB),心房利钠素(BNP)值均有明显增高,LVEF明显降低,与对照组比较,差别有显著性差异(P<0.001)。结论:CK-MB、BNP、左心室射血分数(LVEF)可作为高原肺水肿继发急性呼吸窘迫综合征患者的心脏功能障碍的重要检测指标,对判断病情有重要意义。
Objective: To analyze the changes of cardiac markers and cardiac function in patients with acute respiratory distress syndrome (ARDS) complicated by altitude pulmonary edema (HAPE). Methods: Twenty-four patients with pulmonary hypertension secondary to respiratory distress syndrome admitted in our hospital over the past five years were enrolled as experimental group. Twenty-four healthy volunteers were recruited as control group. Results: The CK-MB and BNP in 24 experimental groups were significantly higher than those in the control group (P < 0.001). Conclusions: CK-MB, BNP and LVEF can be used as important indexes of cardiac dysfunction in patients with acute respiratory distress syndrome secondary to pulmonary edema in high altitude, which is of great significance in judging the disease.