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在小鼠接种小鼠宫颈未分化鳞状细胞癌14号(U_(14)细胞)后的25 d时间中,动态地观察了宿主淋巴组织的重量、组织学和组织化学变化。结果发现,5～15 d细胞免疫增强,10 d最强,20d减弱。体液免疫增强从10 d后开始并持续到实验结束,20 d反应最强。提示U_(14)细胞能诱导宿主产生免疫应答,早期以细胞免疫为主,后期以体液免疫为主。
The weight, histology and histochemical changes of the host lymphoid tissue were dynamically observed during a 25-day period after inoculation of the mouse cervical Undifferentiated Squamous Cell Carcinoma No. 14 (U_ (14) cells). The results showed that 5 to 15 days increased cellular immunity, strongest on the 10th, 20d weakened. Humoral immune enhancement began after 10 days and continued until the end of the experiment, 20 d the strongest response. It is suggested that U_ (14) cells can induce the host to produce an immune response, mainly in the early stage of cellular immunity, and humoral immunity in the later period.