目的分析合肥市1997~2005年乙型肝炎流行概况,为今后乙肝防治工作提供科学依据。方法用描述性流行病学研究方法对1997~2005年合肥市乙型肝炎疫情资料进行分析。结果1997~2005年合肥市共报告乙型肝炎16 351例,年平均发病率为41.93/10万,总体呈稳中略降的趋势。20~44岁组为高发年龄组,发病数占总病例数的48.65%。15岁以下年龄组发病率下降明显。职业分布以农民为最高。结论合肥市1997~2005年乙型肝炎发病比较平稳,略成下降趋势,成人乙肝疫苗接种工作仍应重视和加强。 Objective To analyze the prevalence of hepatitis B in Hefei from 1997 to 2005, and provide a scientific basis for prevention and control of hepatitis B in the future. Methods Descriptive epidemiological methods were used to analyze the Hepatitis B outbreak data from 1997 to 2005 in Hefei City. Results A total of 16 351 hepatitis B cases were reported in Hefei City from 1997 to 2005, with an average annual incidence of 41.93 / 100 000, showing a slight decrease in overall stability. The 20-44 age group was the high incidence age group, the incidence of which accounted for 48.65% of the total number of cases. Incidence in the age group of 15 years of age decreased significantly. Occupation distribution to farmers as the highest. Conclusion The incidence of hepatitis B in Hefei from 1997 to 2005 was relatively stable with a slight downward trend. Adult hepatitis B vaccination should still be emphasized and strengthened.