扑翼样震颤(Asterixis)的特征是保持姿势的肌肉紧张性收缩的间歇性短暂松弛.这种神经症状常与肝、肾或肺部疾病或药物中毒引起的弥漫性脑病有关,单侧扑翼样震颤可能由局灶性脑病引起.Adalns等(1978)报告1例难治性癫癎病人用丙戊酸钠后产生扑翼样震颤,该患者没有肝功能异常的证据,但同时合并用扑癎酮与苯巴比土.本文报告2例患者的所见.例1:男性,29岁,顽固性部分复什性发作与全身性强直—阵挛发作,用苯妥因和扑癎酮,每天有3-8次发作,1979年2月加用丙戊酸钠15毫克/公斤体重/日,5个月后增至50毫克/公斤/日,精神转佳,但仍有发作,7月加用醋唑磺胺500毫克/日, Asterixis is characterized by intermittent short-term relaxation of the tense contraction of muscles that maintain posture, which is often associated with diffuse encephalopathy caused by liver, kidney or lung disease or drug intoxication, Tremor-like tremor may be caused by focal encephalopathy.Adalns et al. (1978) reported a flapping-wing tremor after valproate in one intractable epilepsy patient without evidence of liver dysfunction but in combination Chlordone and phenobarbital This article reports findings in 2 patients.Example 1: Male, 29 years old with refractory partial recurrent seizures and generalized tonic-clonic seizures, with phenytoin and puerarin, 3-8 episodes per day, February 1979 plus sodium valproate 15 mg / kg body weight / day, 5 months after the increase to 50 mg / kg / day, the spirit of the better, but there are still seizures, July Add acetochlor sulfonamide 500 mg / day,