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目的:探讨剖宫产患者术后感染的发生与抗菌药物给药时机。方法:选取2012年8月—2014年12月期间接受治疗的剖宫产产妇90例,将其随机分为对照组和实验组,对照组产妇术后给予头孢唑啉治疗,实验组产妇术前给予头孢唑啉治疗,分析两组产妇的临床疗效。结果:实验组产妇的子宫复旧不佳例数、住院天数和术后感染率分别为1例、(4.9±1.2)d和2.22%,均明显低于对照组为4例、(7.2±1.5)d和6.67%(P<0.05);两组产妇术后的血清PCT、CRP、IL-6、TNF-α水平值均明显高于术前(P<0.05);实验组产妇术后的血清PCT、CRP、IL-6、TNF-α水平值均明显低于对照组(P<0.05)。结论:术前给予头孢唑啉抗感染治疗可降低产妇术后感染的发生,有助于产妇的康复。
Objective: To investigate the incidence of postoperative infection and antimicrobial drug delivery in patients with cesarean section. Methods: Ninety cases of cesarean section received treatment from August 2012 to December 2014 were randomly divided into control group and experimental group. In the control group, cefazolin treatment was given to the mothers postoperatively. In the experimental group, maternal preoperative Give cefazolin treatment, analysis of the clinical efficacy of two groups of maternal. Results: In the experimental group, the number of maternal uterine poor patients, hospital stay and postoperative infection rate were 1 case (4.9 ± 1.2) days and 2.22%, respectively, which were significantly lower than those in the control group (4 cases, 7.2 ± 1.5) d and 6.67% (P <0.05). The levels of serum PCT, CRP, IL-6 and TNF-αin the two groups were significantly higher than those before operation (P <0.05) , CRP, IL-6, TNF-α levels were significantly lower than the control group (P <0.05). Conclusion: Preoperative cefazolin anti-infective treatment can reduce the occurrence of postoperative maternal infection, contribute to maternal rehabilitation.