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目的 :观察卡孕栓在 9～ 12周妊娠人工流产术前阴道用药的宫颈扩张作用和镇痛作用。方法 :将病例 32 0例随机分成A、B两组。A组 :卡孕栓组 ,于人工流产术前 3h阴道后穹窿置卡孕栓 1mg。B组 :对照组 ,术前不给予任何药物 ,给予口头安慰。记录每例患者宫颈的扩张程度、腹痛、出血及副作用。结果 :卡孕栓组较对照组有明显的宫颈扩张及镇痛作用 ,而且出血量明显减少 ;卡孕栓组较对照组腹泻等胃肠道副反应的发生率高 ,但多为一过性 ,有明显的首过效应 ,无需特殊处理。结论 :卡孕栓在 9～ 12周妊娠人工流产术前阴道用药有较强的宫颈扩张及镇痛作用 ,而且出血量明显减少 ,使人工流产术成为一种安全、可靠、简便的无痛手术。
Objective: To observe the cervical dilation effect and analgesic effect of carbamazepine vaginal administration before artificial abortion of 9 ~ 12 weeks gestation. Methods: 32 cases were randomly divided into A and B groups. Group A: Kaposi suppository group, 3 h before induced vaginal fornix vaginal fornix card pregnant suppository 1mg. Group B: control group, no medication was given before operation, and oral comfort was given. Record each patient’s cervical dilatation, abdominal pain, bleeding and side effects. Results: Kaposi suppository group had obvious cervical dilatation and analgesia effect compared with the control group, and the amount of bleeding was significantly reduced. The incidence of gastrointestinal side effects such as diarrhea was higher in the Kapushuan group than in the control group, but mostly transient , There is a clear first pass effect, without special treatment. CONCLUSION: Kaposi suppository has good cervical dilatation and analgesia before vaginal use of artificial abortion during 9 ~ 12 weeks of gestation, and the amount of bleeding is significantly reduced, making artificial abortion a safe, reliable and easy painless operation .