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目的:利用药物利用评价(drug use evaluation,DUE)的赋权逼近理想值排序法(technique for order preference by similarity to an ideal solution,TOPSIS)进行左氧氟沙星的预防用药评价。方法:结合DUE建立评价标准,运用基于属性的层次模型(attribute hierarchical mode,AHM)赋权法计算评价指标的相对权重,并运用TOPSIS进行数据处理以评价各医嘱与完全合理医嘱的距离,计算合理医嘱的比例,以评价抗菌药物预防用药合理性。结果:64份医嘱中完全合理的医嘱占66%(C_i=1,42份),基本合理医嘱占23%(0.8>C_i>0.6,15份),不合理医嘱占11%(C_i<0.6,7份)。结论:运用基于DUE的加权AHM的TOPSIS法对左氧氟沙星预防用药进行合理性评价是合理可行的。武汉科技大学附属普仁医院在左氧氟沙星的预防用药基本合理,但仍需改进。
OBJECTIVE: To evaluate the prophylaxis of levofloxacin by using the technique for order preference by similarity to an ideal solution (TOPSIS) for drug use evaluation (DUE). Methods: Based on DUE, evaluation criteria were established, and the relative weights of evaluation indexes were calculated by attribute-based AHM (weighted hierarchical model), and TOPSIS was used to evaluate the distance between each order and the full reasonable order. The calculation was reasonable The proportion of medical advice to evaluate the rational use of antimicrobial agents. Results: Among 64 orders, 66% (C_i = 1,42) were reasonable medical orders, 23% (0.8> C_i> 0.6), 11% were unreasonable orders (C_i <0.6, 7 copies). Conclusion: It is reasonable and feasible to evaluate the prophylaxis of levofloxacin using TOPSIS method based on weighted AHM based on DUE. Preventive treatment of levofloxacin at Putin Hospital affiliated to Wuhan University of Science and Technology is basically reasonable, but still needs improvement.