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目的 :观察人体血液中红细胞抗氧化蛋白 (HRPRP)、SOD酶、GSH -PX酶在间歇性低氧暴露后的变化 ,观察抗氧化系统在间歇性低氧暴露后的反应是否有利于运动能力的提高。方法 :男性大学生 1 5名随机分成对照组和实验组 ,两组从事相同身体活动 ,实验组每天安静状态下间歇吸低氧 (浓度 1 4 %～ 1 0 %) 5 0～ 6 0分钟 ,连续 4周。两组均在实验开始前、结束后按Bruce方案进行力竭运动 ,并在安静和运动后取血测试HRPRP、SOD、GSH -PX、MDA。结果 :间歇性低氧暴露后 ,HRPRP含量和红细胞抗氧化酶SOD、GSH -PX活性在安静时和力竭运动后明显提高 ,运动时间延长 ,最大吸氧量增加。结论 :间歇性低氧暴露有助于增强红细胞抗氧化能力 ,改善和提高运动能力。
OBJECTIVE: To observe the changes of red blood cell antioxidant protein (HRPRP), SOD enzyme and GSH-PX enzyme in human blood after intermittent hypoxic exposure and to observe whether the antioxidant system response to intermittent hypoxic exposure is beneficial to exercise capacity improve. Methods: Fifteen male college students were randomly divided into control group and experimental group. The two groups were engaged in the same physical activity. The experimental group received intermittent hypoxia (concentration 14% -100%) intermittently for 60-60 minutes in a quiet state every day for continuous 4 weeks. Before and after the start of the experiment, both groups were subjected to exhaustive exercise according to the Bruce protocol. Blood samples were taken for HRPRP, SOD, GSH-PX and MDA after resting and exercising. Results: After intermittent hypoxia exposure, the activities of HRPRP, SOD and GSH-PX in red blood cells increased significantly after resting and after exhaustive exercise, prolonged exercise time and maximum oxygen uptake. Conclusion: Intermittent hypoxic exposure helps to enhance the antioxidant capacity of red blood cells, improve and improve exercise capacity.