[目的]探讨精神分裂症患者自尊水平与敌意归因偏向及孤独感的相关性.[方法]选取2013年2月至2017年8月于本院就诊的147例精神分裂症患者的临床资料,根据罗森伯格自尊量表(SES)评分将其分为较高自尊水平组(H组,n =88)和较低自尊水平组(L组,n =59),分别以中文版模棱两可、目的和敌意问卷(AIHQ-C)及中文版孤独量表(UCLA)评测敌意归因偏向及孤独感,同时作阳性和阴症状量表(PANSS)测评,比较两组敌意归因偏向、自尊水平及孤独感的差异,分析患者自尊水平与敌意归因偏向和孤独感的相关性.[结果]H 组UCLA评分显著低于L组,差异具有统计学意义(P <0.05);AIHQ-C THB、AIHQ-C TBB、AIHQ-C TAB 评分显著高于L组,差异具有统计学意义(P <0.05).本研究中147例患者中无孤独感患者41例(27.87%),较少孤独感患者89例(60.54%),有时有孤独感患者17例(11.56%),较少孤独感患者所占比例显著高于无孤独感及有时有孤独感患者,差异具有统计学意义(P <0.05).Pearson线性相关性分析结果显示,精神分裂症患者SES评分与AIHQ-C THB、AIHQ-C TBB、AIHQ-C TAB、UCLA评分、PANSS总分、阳性症状分、阴性症状分均呈负相关性(均 P <0.05);患者UCLA评分与AIHQ-C THB、AIHQ-C TBB、AIHQ-C TAB、UCLA评分、PANSS总分、阳性症状评分、阴性症状评分均呈显著正相关性(均 P <0.05).[结论]精神分裂症患者自尊水平较低的患者存在明显的敌意归因偏向和较高的孤独水平,且自尊水平与敌意归因偏向及孤独水平呈负相关,而孤独水平与敌意归因偏向呈正相关,说明低自尊水平和(或)孤独感较强患者更易出现敌意、责备、攻击等倾向.“,”[Objective]To explore the relationship between self-esteem,hostility attribution bias and loneliness in schizophrenic patients.[Methods]The clinical data of 147 schizophrenic patients from February 2013 to August 2017 in our hospital were selected.According to the Rosenberg Self-esteem scale(Rosenberg Self-esteem scale) score,they were divided into two groups:high self-esteem group(group H)and lower self-esteem group(group L),the Chinese version of ambiguity,purpose and hostility questionnaire(AIHQ-C)and the Chinese version of Lonely scale(UCLAA)were used to evaluate the hostility attribution bias and loneliness.At the same time,the positive and negative symptom scale(PANSS)was used to compare the differences of hostility attribution bias, self-esteem level and loneliness between the two groups,and to analyze the correlation between the self-esteem lev-el and hostility attribution bias and loneliness.[Results]Loneliness scores of the group H were significantly lower than those of the group L,the difference was statistically significant(t = 2.6511,P <0.05);AIHQ-C,HB,BB and AB of the group H were significantly lower than those of the group L,the difference was statistically signifi-cant(t = 2.9049,t = 3.7436,t = 3.1781,P <0.05);The Pearson correlation analysis showed that patients with schizophrenia SES and UCLA score,AIHQ-C HB,BB,AB,PANSS total score,positive symptoms,negative symptoms were negatively correlated(r = -0.337,-0.176,-0.167,-0.258,-0.198,-0.291,-0.208,and P <0.05);the spirit of in patients with UCLA score and AIHQ-C HB,BB,AB division,PANSS total score, positive symptoms,negative symptoms were positively correlated(r =0.193,0.336,0.397,0.346,0.364,0.224,P<0.05).[Conclusion]The patients with lower self-esteem have obvious hostile attributional bias and higher loneli-ness level.The self-esteem level is negatively correlated with hostile attribution bias and loneliness level,while loneliness level is positively correlated with hostile attribution bias,indicating that patients with low self-esteem level and /or strong loneliness are more prone to hostility,blame,aggression and so on..