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为进一步探讨大鼠旁巨细胞外侧核（ＰＧＣＬ）在呼吸调控中的作用，采用细胞外记录法，探查了在麻醉、自主呼吸下的１４只ＳＤ大鼠的ＰＧＣＬ尾半侧（ｃＰＧＣＬ）神经元的自发放电类型，分析了呼吸相关神经元（ＲＲＮｓ）的放电样式和分布。结果：在ｃＰＧＣＬ区共记录到２３７个自发放电神经元，其中ＲＲＮｓ３９个，非呼吸相关神经元（ＮＲＲＮｓ）１９８个。ＮＲＲＮｓ主要呈紧张性放电样式（ｎ＝１７８）。ＲＲＮｓ中，吸气神经元（ＩＮｓ）、呼气神经元（ＥＮｓ）、跨时相神经元（ＰＳＮｓ）各为２４、１２和３个。ＩＮｓ的放电样式为递增型（２０／２４个）、稳定型或钟型（４／２４个）；ＥＮｓ为递减型（７／１２个）、稳定型或钟型（５／１２个）；ＰＳＮｓ有吸气－呼气（ＩＥＮｓ，２／３个）和呼气－吸气（ＥＩＮｓ，１／３个）跨时相神经元，均为稳定型或钟型放电样式。ＲＲＮｓ主要分布在ｃＰＧＣＬ背外侧份，越近尾端越密集。上述结果提示ＰＧＣＬ是呼吸调控的重要中枢部位之一
In order to further investigate the role of PGCL in respiratory regulation in rats, we used extracellular recording to investigate the effects of PGCL tail cAMP (cPGCL) neurons in 14 SD rats under anesthesia and spontaneous breathing The type and distribution of respiratory-related neurons (RRNs) were analyzed. RESULTS: A total of 237 spontaneous discharge neurons were recorded in cPGCL, including 39 RRNs and 198 non-respiratory related neurons (NRRNs). NRRNs mainly showed a pattern of tension discharge (n = 178). In RRNs, inspiratory neurons (INs), exhaled neurons (ENs) and transphase neurons (PSNs) were 24, 12 and 3, respectively. The discharge patterns of INs are ascending (20/24), stable or bell (4/24), ENs are decreasing (7/12), stable or bell (5/12), PSNs There are inspiratory - expiratory (IENs, 2/3) and expiratory - inspiratory (EINs, 1/3) interphase neurons, both stable or bell-shaped discharge patterns. RRNs mainly distributed in the dorsolateral part of cPGCL, the closer the more dense the tail. The above results suggest that PGCL is one of the important central parts of respiratory regulation