JM是来自人胸腺不成熟T细胞的急性淋巴细胞白血病细胞系。作者用SAC刺激的人外周血纯化B淋巴细胞和小鼠脾细胞增殖为模型,观察了JM细胞培养上清(SPN_(JM))对人B淋巴细胞和小鼠脾细胞增殖的免疫调节作用。发现具有T细胞抑制活性的SPN_(JM)对人和小鼠B淋巴细胞的增殖具有促进作用。在无SAC诱 JM is an acute lymphoblastic leukemia cell line derived from human thymus immature T cells. The authors used SAC stimulated human peripheral blood purified B lymphocytes and mouse spleen cell proliferation as a model to observe the JM cell culture supernatant (SPN_ (JM)) on human B lymphocyte and mouse spleen cell proliferation immunoregulatory effect. SPN_ (JM) with T cell suppressive activity was found to promote the proliferation of human and mouse B lymphocytes. No SAC lure