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目的:分析血液透析法(HD)联合血液灌流法(HP)治疗重症有机磷农药中毒的治疗效果。方法:使用一次性灌流治疗仪器进行血液灌注,肝素化之前要预冲好灌流器;为患者构建静脉通路时,使用的器械为静脉双腔股式插管。在对患者血流量进行调整时,将其生命体征作为标准。HD治疗的方法如下:在周中透析2～4次,每次透析550mL/min的液量,200～300mL/min的血流量,透析时间为120min。结果:30例患者中,有29例治愈,其余1例患者因中枢循环衰竭以及呼吸衰竭而死亡;治疗的总有效率为96.67%。结论:HP联合HD是治疗中毒患者的有效方法,值得临床推广使用。
Objective: To analyze the therapeutic effect of hemodialysis (HD) combined with hemoperfusion (HP) on severe organophosphorus pesticide poisoning. Methods: A one-time perfusion therapy instrument was used to perform blood perfusion. Before heparinization, a pre-perfusion cartridge was prepared. For venous access to patients, the instrument used was a venous double lumen cannula. When adjusting the patient’s blood flow, its vital signs are used as a standard. HD treatment as follows: dialysis in the week 2 to 4 times, each dialysis 550mL / min volume, 200 ~ 300mL / min blood flow, dialysis time was 120min. Results: Of the 30 patients, 29 were cured and the remaining 1 patient died of central circulatory failure and respiratory failure. The total effective rate was 96.67%. Conclusion: HP combined with HD is an effective treatment for patients with poisoning, worthy of clinical promotion.