论文部分内容阅读
目的观察厄贝沙坦联合氢氯噻嗪治疗中、重度高血压的疗效。方法60例中、重度高血压患者每日上午给予厄贝沙坦150~300 mg。1次/d口服,氢氯噻嗪12.5 mg1次/d口服,连续8周,用药前后监测血压、心率、血钾、肾功能、血糖及血脂。结果总有效率96.7%,对心率、血钾、肾功能、糖代谢、脂代谢均无明显影响,(P>0.05)。结论厄贝沙坦与氢氯噻嗪联合治疗中、重度高血压疗效显著,不良反应少,临床值得推广使用。
Objective To observe the efficacy of irbesartan and hydrochlorothiazide in the treatment of moderate and severe hypertension. Methods 60 patients, patients with severe hypertension were given irbesartan 150 ~ 300 mg every morning. 1 / d oral, hydrochlorothiazide 12.5 mg 1 times / d orally for 8 weeks, before and after treatment monitoring of blood pressure, heart rate, serum potassium, renal function, blood glucose and blood lipids. The results of the total efficiency of 96.7%, heart rate, serum potassium, renal function, glucose metabolism, lipid metabolism had no significant effect (P> 0.05). Conclusion Irbesartan combined with hydrochlorothiazide in the treatment of moderate and severe hypertension has obvious curative effect and few adverse reactions, so it is worth to be used clinically.