华支睾吸虫病是亚洲东部的一种感染人的寄生虫病 ,主要分布在中国、日本、韩国和越南北部。传统的病原学诊断方法存在着一些弊病 ,免疫诊断抗原的提纯以及免疫诊断方法的改进则提高了诊断的敏感性和特异性 ,为华支睾吸虫病的诊断提供了科学的辅助手段。本文对华支睾吸虫病的免疫诊断抗原、诊断方法以及在分子生物学方面的研究进展作一简要综述 Clonorchis sinensis is a human-induced parasitic disease in eastern Asia, mainly in China, Japan, South Korea and northern Vietnam. The traditional methods of etiological diagnosis have some disadvantages. The purification of immunological diagnostic antigens and the improvement of immunological diagnostic methods improve the sensitivity and specificity of diagnosis, and provide a scientific auxiliary method for the diagnosis of Clonorchiasis. This article gives a brief overview of immunodiagnostic antigens, diagnostic methods and molecular biology in the diagnosis of Clonorchiasis