颅内感染是神经科的常见病症,患者常有颅内高压、意识障碍及多种严重并发症,存活者仍可遗留痴呆、癫痫、瘫痪和颅神经麻痹等后遗症,加强对该类疾病的诊治管理具有重要的临床意义。在临床工作中,由于抗生素滥用、病原体的耐药性增强及脑脊液(CSF)培养的低阳性率导致了颅内感染不 Intracranial infection is a common neurological disease, patients often have intracranial hypertension, disturbance of consciousness and a variety of serious complications, survivors may still be dementia, epilepsy, paralysis and cranial nerve paralysis and other sequelae, to strengthen the diagnosis and treatment of such diseases Management has important clinical implications. In clinical practice, intracranial infections are not due to antibiotic abuse, increased pathogen resistance, and low positive rates of cerebrospinal fluid (CSF) culture