已知慢性支气管炎,肺气肿和肺癌等与吸烟有关的疾病其血管紧张素转化酶(ACE)的活性减低,本文为证明长期吸烟者的 ACE 水平而检测了40名吸烟健康者,并以42名不吸烟的健康者作对照。吸烟组每天吸含中性尼古丁香烟15支以上,至少10年。血清 ACE活性是按照 Friedland 和 Silverstein 用 Hippuryl-L-histidyl-L-leucine 作底物的方法进行荧光检测。结果吸烟组的血清 ACE 平均值为31.1±8.14μmol/L,不吸烟组为40.8±10.78μmol/L,两组差异 It is known that cigarette smoking-related diseases such as chronic bronchitis, emphysema and lung cancer have a reduced activity of angiotensin-converting enzyme (ACE). In this paper, 40 smokers were tested for ACE levels in long-term smokers, 42 non-smokers healthy control. Smoking group inhaled more than 15 neutral nicotine cigarettes a day for at least 10 years. Serum ACE activity was determined by the method of Friedland and Silverstein using Hippuryl-L-histidyl-L-leucine as a substrate. Results The mean serum ACE of the smoker group was 31.1 ± 8.14μmol / L and that of the non-smoker group was 40.8 ± 10.78μmol / L, with a significant difference between the two groups