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在影响妇科恶性肿瘤预后的诸多因素中,肿瘤细胞的转移已作为重要的独立预后因素引起广泛重视。近年来的研究显示,转移抑制基因的丢失是导致肿瘤转移的一个重要方面,KiSS-1基因是近年来克隆的一个新的肿瘤转移抑制基因,研究表明,人类多种恶性肿瘤转移与KiSS-1表达缺失有关,且可以为
Among the many factors affecting the prognosis of gynecologic malignancies, the metastasis of tumor cells has drawn great attention as an important independent prognostic factor. In recent years, studies have shown that the loss of metastasis suppressor genes is an important aspect of tumor metastasis. KiSS-1 gene is a novel gene transfer suppressor gene cloned in recent years. Studies have shown that many metastatic human malignancies are associated with KiSS-1 Lack of expression, and can be