0引言核黄素是一种重要的黄素类物质,在体内形成两种主要衍生物———黄素单核苷酸FMN和黄素腺嘌呤二核苷酸FAD,作为黄素酶的辅酶参与体内一系列生化代谢过程。近年来,机体内核黄素缺乏与肿瘤的发生,尤其是与食管鳞癌发生的关系日益受到关注。研究发现食管鳞癌高发区河北磁县居民 0 Introduction Riboflavin is an important flavonoid that forms two major derivatives of the body, flavin mononucleotide FMN and flavin adenine dinucleotide FAD, and participates in the body as a coenzyme of flavinase A series of biochemical metabolic processes. In recent years, the body of riboflavin deficiency and tumor occurrence, especially esophageal squamous cell carcinoma is increasingly concerned about the occurrence. Study found that high incidence of esophageal squamous cell Cixian residents in Hebei