术前胃活检诊断神经内分泌肿瘤类型标准的探讨

来源 :诊断病理学杂志 | 被引量 : 0次 | 上传用户:honeysword
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
不同类型的胃神经内分泌肿瘤(GNET)其治疗手段不同,因此在手术前对GNET类型的正确诊断十分重要。本文收集52例胃神经内分泌肿瘤,通过对其临床病理特点及患者随访的观察,提出GNET临床病理类型。Ⅰ型胃泌素依赖型类癌:可单发及多发,肿瘤的发生与胃泌素有关,生物学行为多为良性。治疗行息肉切除术或胃窦切除术,预后好。Ⅱ型非胃泌素依赖型类癌:多为散在单发,肿瘤发生与冒犯素无关,肿瘤较Ⅰ型恶性程度高,治疗行胃大部切除术。Ⅲ型胃神经内分泌癌:高度恶性GNET肿瘤,肿瘤低分化,治疗行胃切除术及术后综合化疗,预后差。本文重点对手术前胃内镜诊断GNET不同类型的标准进行了探讨。 Different types of gastric neuroendocrine tumors (GNET) have different treatment methods, so it is very important to correctly diagnose GNET types before surgery. In this paper, 52 cases of gastric neuroendocrine tumors were collected. Clinical pathological types of GNET were proposed through observation of their clinicopathological features and follow-up of patients. I-type gastrin-dependent carcinoid: can be single and multiple, the occurrence of tumor and gastrin related biological behavior mostly benign. Treatment with polypectomy or gastrectomy has a good prognosis. Type II non-gastrin-dependent carcinoid: mostly scattered in a single, tumor occurrence has nothing to do with the offensive, the tumor is more malignant than the type I, the treatment line subtotal gastrectomy. Type III Gastric Endocrine Carcinoma: Highly malignant GNET tumors, poorly differentiated tumors, gastrectomy and postoperative comprehensive chemotherapy, and poor prognosis. This article focuses on the discussion of different types of criteria for preoperative GERT examination of gastric endoscopy.
其他文献