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目的比较限制性输血与开放性输血在重型颅脑损伤患者中的应用价值。方法将重型颅脑创伤患者63例随机分为限制性输血组30例和开放性输血组33例。限制性输血组于血红蛋白<70g/L时开始输注去白红细胞悬液以维持血红蛋白浓度于相应的水平,一次输注2~4个单位;开放性输血组于血红蛋白<100g/L时开始输注去白红细胞悬液以维持血红蛋白浓度于相应的水平,输血剂量同限制性输血组。比较2组患者输血率、人均输血量、输血不良反应及血栓栓塞事件发生率。结果限制性输血组输血率、人均输血量、输血不良反应及血栓栓塞事件发生率均显著低于开放性输血组(P<0.05)。结论限制性输血在重型颅脑损伤患者的输血治疗中具有重要的临床价值,既有助于节约血资源,又减少了输血相关不良反应的发生率,而且受到了患者、医护人员和血站工作人员的欢迎,获得了明显的经济和社会效益,值得临床推广应用。
Objective To compare the value of limited blood transfusion and open transfusion in patients with severe craniocerebral injury. Methods 63 patients with severe traumatic brain injury were randomly divided into a restricted transfusion group of 30 cases and open transfusion group of 33 cases. In the restricted blood transfusion group, transfused white blood cell suspension was started when hemoglobin was less than 70g / L to maintain the hemoglobin concentration at the corresponding level, with 2 to 4 units infused at one time. The open transfusion group started to lose when hemoglobin was below 100g / L Note white blood cell suspension to maintain the hemoglobin concentration in the corresponding level, transfusion dose with the restricted transfusion group. Blood transfusion rate, transfusion volume per capita, adverse transfusion reactions and incidence of thromboembolism were compared between the two groups. Results The blood transfusion rate, transfusion volume, transfusion adverse reactions and the incidence of thromboembolism in the restricted transfusion group were significantly lower than those in the open transfusion group (P <0.05). Conclusion Restrictive transfusion has important clinical value in the treatment of patients with severe traumatic brain injury, which not only helps save blood resources but also reduces the incidence of transfusion-related adverse reactions, and is also affected by patients, medical staff and blood bank work Personnel welcome, access to significant economic and social benefits, it is worth clinical application.