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目的探讨左旋氨氯地平治疗高血压的临床疗效。方法选取2015年1—5月贵州医科大学第二附属医院收治的高血压患者200例,按随机数字表法分为对照组与观察组,各100例。观察组患者予以左旋氨氯地平治疗,对照组患者予以尼群地平治疗。观察两组患者临床疗效、不良反应发生情况及治疗前后生活质量评分。结果两组患者临床疗效比较,差异无统计学意义(P>0.05);观察组患者不良反应发生率低于对照组,差异有统计学意义(P<0.05);治疗前两组患者躯体功能、角色功能、社会功能、情绪功能及总体评分比较,差异无统计学意义(P>0.05),治疗后观察组患者躯体功能、角色功能、社会功能、情绪功能及总体评分高于对照组,差异有统计学意义(P<0.05)。结论左旋氨氯地平治疗高血压的临床疗效显著,可提高患者的生活质量,且不良反应少。
Objective To investigate the clinical efficacy of levamlodipine in the treatment of hypertension. Methods From January to May 2015, 200 cases of hypertensive patients admitted to the Second Affiliated Hospital of Guizhou Medical University were divided into control group and observation group according to the random number table method, each with 100 cases. Patients in the observation group were treated with levamlodipine, and patients in the control group were treated with nitrendipine. Clinical efficacy, adverse reactions and quality of life before and after treatment were observed in two groups. Results There was no significant difference in clinical efficacy between the two groups (P> 0.05). The incidence of adverse reactions in the observation group was lower than that in the control group (P <0.05). Before treatment, the body function, (P> 0.05). After treatment, the body function, the role function, the social function, the emotional function and the overall score in the observation group were higher than those in the control group, the difference was statistically significant Statistical significance (P <0.05). Conclusion L-amlodipine treatment of hypertension clinical efficacy significantly, can improve the quality of life of patients with fewer adverse reactions.