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[目的]探讨在高发区高危人群中发现早期癌及癌前病变的有效途径。[方法]林州市“食管癌早诊早治示范基地”依据中国癌症基金会对基地高危人群筛查方案,2005~2007年在林州市合涧镇的目标人群中按照顺应性70%的要求,对8432例40~69岁的6048例人群进行了内镜+食管碘染色+指示性活检和贲门脊根部活检。[结果]发现癌症患者100例,其中食管癌38例,贲门癌54例,胃癌7例,下咽癌1例,其中早期癌83例,检出率1.65%;癌前病变(高级别上皮内瘤变)148例,检出率2.45%。[结论]提高高危人群对癌症的认知度,推广食管碘染色和贲门脊根部常规活检技术,是提高食管贲门癌早期发现的关键。
[Objective] To explore an effective way to detect early cancers and precancerous lesions in high-risk areas of high incidence areas. [Methods] Linzhou City, “early diagnosis and treatment of early diagnosis and treatment of esophageal base” based on the China Cancer Foundation screening program for high-risk groups at base, from 2005 to 2007 in Linzhou City, the town of Jianjian target population in accordance with compliance 70 % Of the 8432 cases of 40 to 69-year-old population of 6048 cases of endoscopic + esophageal iodine staining + indicative biopsy and cardiac biopsy. [Results] 100 cases of cancer patients were found, including 38 cases of esophageal cancer, 54 cases of cardia carcinoma, 7 cases of gastric cancer and 1 case of hypopharyngeal carcinoma, of which 83 cases were early carcinoma with a detection rate of 1.65%. Premalignant lesions Tumor) 148 cases, the detection rate of 2.45%. [Conclusion] It is the key to improve the early detection of esophagus and cardia cancer to improve the awareness of cancer in high-risk groups, to promote the esophageal iodine staining and routine biopsy of cardia and spinal cord.