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目的调查输血传播病毒(TTV)在沙眼衣原体感染者中的感染状况,探讨TTV的传播途径。方法2003年1月至2004年6月新疆维吾尔自治区人民医院等2家医院在TTVORF1保守区设计引物,建立套式聚合酶链反应(PCR),检测46例沙眼衣原体感染者和34例普通体检人群血清、宫颈分泌物中TTV-DNA。结果在46例沙眼衣原体感染者血清、分泌物中TTV-DNA阳性率分别为34·8%、32·6%,而普通体检人群血清、分泌物TTV-DNA阳性率为6·3%、3·1%,两组比较差异有非常显著性意义(P(0·01)。结论沙眼衣原体感染者是TTV感染的高危人群,性接触是TTV传播的重要途径之一。
Objective To investigate the infection status of transfusion transmitted virus (TTV) in Chlamydia trachomatis infection and to explore the transmission of TTV. Methods From January 2003 to June 2004, two hospitals including People’s Hospital of Xinjiang Uygur Autonomous Region were used to design primers in TTVORF1 conservative region. A polymerase chain reaction (PCR) was performed to detect 46 cases of Chlamydia trachomatis infection and 34 cases of general medical examination Serum, TTV-DNA in cervical secretions. Results The positive rates of TTV-DNA in serum and secretions of the 46 cases of Chlamydia trachomatis infection were 34.8% and 32.6% respectively, while the positive rate of TTV-DNA in sera and secretions was 6.3% and 3 · 1%, there was a significant difference between the two groups (P (0.01) .Conclusion Chlamydia trachomatis infection is a high risk population of TTV infection, sexual contact is one of the important ways of TTV transmission.