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目的:观察针刺推拿加开塞露治疗抗精神病药物所致便秘的疗效.方法:将240例患者随机分为A组,B组,C组,D组各60例,A组采用针刺推拿加开塞露治疗,B组采用针刺治疗,C组用推拿治疗,D组用开塞露治疗.结果:A组有效率为98.3%,B组有效率95.0%,C组有效率为91.7%,D组有效率60.0%,经χ2检验4组疗效有显著性差异,A组与B组、C组相比(P＜0.05),A组与D组相比(P＜0.01).4组治疗效应产生的时间((-χ)±S):A组2.41±1.87 h,B组2.47±1.89h,C组9.81±6.12h,D组15.13±6.17h,经t检验,A、B组效应时间差异有显著性(P＜0.05),A、C组差异有显著性(P＜0.05),A、D组差异有极显著性(P＜0.01),B、C组差异不显著(P＞0.05).结论:针刺与推拿均有较好的疗效,但针推加开塞露综合治疗效果最佳,且通便快.,Objective: To observe the therapeutic results of Acupuncture and Tuina combining with laxative suppository in treating constipation caused by antisychotic drugs. Methods: 240 patients were randomly divided into Group A, B, C, and D, 60 in each group. Group A were treated with Acupuncture and Tuina combining with laxative suppository, Group B with Acupuncture, Group C with Tuina and Group D with laxative suppository. Results: The effective rate in Group A was 98.3%, Group B 95.0%, Group C 91.7% and Group D 60.0%. Univariate χ2 was used for analysis. There were significant differences among the 4 groups. Group A was compared with Group B and C (P＜0.05) and compared with D (P＜0.01). The efficacy time( (-χ)± S) was 2.41 ± 1.87h in Group A, 2.47 ± 1.89h in Group B,9.81 ± 6.12h in Group C and 15.13 ± 6.17h in Group D. The t-test was used for analysis. The efficacy time was significant different in Group A and B (P＜0.05), significant different in Group A and C (P＜0.05), marked different in Group A and D (P＜0.01) and no significant different in Group B and C (P＞0.05). Conclusion: Acupuncture and Tuina were effective, yet Acupuncture and Tuina combined with laxative suppository were more effective, and induce quick defecation.