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目的观察凝血酶对乳腺癌改良根治术后引流液的治疗效果。方法86例术后第4天引流量>50 ml/d的乳腺癌患者分为两组,实验组45例从引流管注入凝血酶,对照组41例不注入凝血酶,观察注入凝血酶后48 h内总的引流量、引流液颜色和皮下积液情况。结果实验组48 h内总的引流量为(204±96)ml,少于对照组(273±112)ml(P<0.01)。实验组皮下积液发生率11.1%,对照组29.3%,前者发生率少于后者(t=3.08,P<0.05)。结论凝血酶可减少乳腺癌改良根治术后创面引流量,降低皮下积液发生率。
Objective To observe the therapeutic effect of thrombin on the drainage of modified radical mastectomy for breast cancer. Methods Eighty-six patients with breast cancer whose drainage volume was> 50 ml / d on the fourth day after operation were divided into two groups. In the experimental group, 45 cases were injected with thrombin from the drainage tube and 41 cases were not injected with thrombin in the control group. h total drainage, drainage fluid color and subcutaneous fluid situation. Results The total drainage volume within 48 h in experimental group was (204 ± 96) ml less than that in control group (273 ± 112) ml (P <0.01). In the experimental group, the incidence of subcutaneous effusion was 11.1% in the control group and 29.3% in the control group, with the former less frequently than the latter (t = 3.08, P <0.05). Conclusion Thrombin can reduce the drainage of wound after modified radical mastectomy and reduce the incidence of subcutaneous effusion.