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目的 :探讨对特异性鼻粘膜激发试验 ( SNPT)阳性的评价方法。方法 :对 3 0例常年性变应性鼻炎患者(鼻炎组 )和 14例正常成年人 (对照组 )进行 SNPT,观察鼻部症状及鼻气道阻力变化。结果 :激发后 ,鼻炎组绝大多数患者在 0 .5～ 3 .0 min内出现鼻痒、喷嚏、流清涕等症状。连续喷嚏 5个以上者占 83 .3 % ,与对照组 ( 2 1.4% )之间有显著性差异 ( P <0 .0 1) ;鼻腔总阻力和激发侧鼻阻力增加比例 ,两组间有明显差异 ,而两组对照液之间无明显差异。结论 :SNPT后 ,若出现明显的鼻部症状 ,激发侧鼻阻力增加 10 0 %以上 ,总鼻阻力增加 40 %以上 ,对SNPT阳性有判断意义
Objective: To investigate the method of evaluating the positive of specific nasal mucosal provocation test (SNPT). Methods: Thirty patients with allergic rhinitis (rhinitis group) and 14 normal adults (control group) underwent SNPT to observe nasal symptoms and nasal airway resistance changes. Results: After the challenge, the majority of patients in the rhinitis group developed nasal itching, sneezing and runny nose clearance within 0.5-3.0 min. There were significant differences (P <0. 01) between the control group and the control group (83.4%) with more than 5 cases of continuous sneezing; Significant differences, but no significant difference between the two control solution. CONCLUSIONS: If obvious nasal symptoms occur after SNPT, the lateral nasal resistance increases by more than 10% and the total nasal resistance increases by more than 40%