论文部分内容阅读
目的:观察肾康注射液治疗CKD对患者免疫功能的影响。方法:选取齐齐哈尔市第一医院2013年1月~2015年1月收治的CKD患者共140例,随机分为观察组和对照组。对照组予常规西医治疗,观察组在对照组基础上,加用肾康注射液进行治疗。治疗前后对两组患者的肾功能、肌酐清除率、24h尿蛋白、T细胞亚群及NK细胞活性等指标进行比较。结果:观察组总有效率为91.43%,显著高于对照组的68.57%(P<0.05)。观察组治疗后Scr、BUN、24h尿蛋白、血清胱抑素C显著低于对照组(P<0.05),血清IgG、CD3~+、CD4~+/CD8~+、NK水平及肾小球滤过率显著高于对照组(P<0.05)。结论:在常规西医治疗的基础上加用肾康注射液可显著改善CKD患者的肾脏功能,提高患者免疫力。
Objective: To observe the effect of Shenkang injection on immune function in patients with CKD. Methods: A total of 140 CKD patients admitted to the First Hospital of Qiqihar from January 2013 to January 2015 were randomly divided into observation group and control group. The control group was given routine Western medicine treatment. The observation group was treated with Shenkang injection on the basis of the control group. Before and after treatment, the renal function, creatinine clearance rate, 24h urinary protein, T cell subsets and NK cell activity were compared between the two groups. Results: The total effective rate in observation group was 91.43%, which was significantly higher than that in control group (68.57%, P <0.05). The levels of Scr, BUN, 24 h urinary protein and serum cystatin C in the observation group were significantly lower than those in the control group (P <0.05). Serum IgG, CD3 +, CD4 + / CD8 +, NK levels and glomerular filtration rate Pass rate was significantly higher than the control group (P <0.05). Conclusion: The traditional Chinese medicine treatment based on the use of Shen Kang injection can significantly improve renal function in CKD patients and improve patient immunity.