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目的探讨中西医结合治疗在救治重度有机磷农药中毒患者中的疗效并分析其机理,方法收治108例重度有机磷农药中毒患者,随机分为研究组和对照组各54例.对照组给予常规洗胃、导泻、有效解毒药物和血液灌流等治疗;研究组在此基础上,应用中药制剂血必净注射液治疗.结果在死亡率、胆碱酯酶活性改善方面.两组患者无显著差异(P>0.05);但在住院时间.乳酸和TNF-α水平改善程度方面.研究组均显著优于对照组(P<0.05).结论在常规西医救治基础上联用血必净注射液的中西医结合治疗,可有效抑制患者炎症反应、改善应激,并在更短时间内达到康复效果.值得在临床推广应用.
Objective To investigate the curative effect of combined traditional Chinese and western medicine in the treatment of patients with severe organophosphorus pesticide poisoning and analyze its mechanism.Methods 108 cases of severe organophosphorus pesticide poisoning were randomly divided into study group and control group of 54 cases.The control group was given routine washing Stomach, catharsis, effective detoxification drugs and hemoperfusion, etc. On the basis of this study, the study group was treated with Xuebijing injection.Results There was no significant difference between the two groups in terms of mortality and cholinesterase activity (P0.05) .However, the length of hospital stay, the degree of improvement of lactic acid and TNF-α levels in the study group were significantly better than those in the control group (P0.05) .Conclusion On the basis of conventional Western medical treatment with Xuebijing injection Integrative Medicine, can effectively inhibit the inflammatory response in patients, improve stress, and in a shorter period of time to achieve rehabilitation effect, it is worth in the clinical application.