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目的探讨红细胞免疫功能与动脉硬化性脑梗塞的关系。方法采用免疫测定法检测20例脑动脉硬化患者、38例动脉硬化性脑梗塞患者、35例健康对照者的红细胞 C3b受体花环率(RBC-C3bRR)和红细胞免疫复合物花环率( RBC- ICR)。结果脑梗塞 RCB-C3b RR低于正常对照组( P<0.001),而RBC-ICR高于正常对照组(P<0.001),红细胞C3b受体活性降低与脑梗塞灶大小呈负相关性(r=-0.65, P<0.01)。结论红细胞免疫功能与动脉硬化性脑梗塞发病有关。
Objective To investigate the relationship between erythrocyte immune function and arteriosclerotic cerebral infarction. Methods RBC-C3bRR and RBC-ICR of 20 patients with cerebral arteriosclerosis, 38 patients with arteriosclerotic cerebral infarction and 35 healthy controls were detected by immunoassay. ). Results The RCB-C3b RR of cerebral infarction was lower than that of the normal control group (P <0.001), while the RBC-ICR of cerebral infarction was higher than that of the normal control group (P <0.001) Correlation (r = -0.65, P <0.01). Conclusion Erythrocyte immune function is related to the pathogenesis of arteriosclerotic cerebral infarction.