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目的研究血尿酸(UA)水平和左室质量指数(LVMI)与高血压病患者1年内急性心血管事件发生率的关系。方法高血压病患者160例,入院时测定UA水平并计算LVMI,统计其1年内急性心血管事件发生情况。结果UA与LVMI显著相关(r=0.23,P<0.05),高UA者及高LVMI者急性心血管事件发生率显著增高(31%vs5%,P<0.05)。结论高血压病患者血UA水平与LVMI相关,高UA及LVMI增高可增加急性心血管事件发生率。
Objective To investigate the relationship between the level of uric acid (UA) and left ventricular mass index (LVMI) and the incidence of acute cardiovascular events within one year in hypertensive patients. Methods 160 patients with hypertension were enrolled. UA levels were measured at admission and LVMI was calculated. The incidence of acute cardiovascular events within one year was calculated. Results UA was significantly associated with LVMI (r = 0.23, P <0.05). The incidence of acute cardiovascular events was significantly higher in patients with high UA and high LVMI (31% vs 5%, P <0.05). Conclusions UA levels in patients with essential hypertension are associated with LVMI, and elevated UA and LVMI may increase the incidence of acute cardiovascular events.