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目的回顾乳腺导管上皮非典型增生(ADH)误诊情况,总结误诊原因,提高诊断水平。方法收集近10年最终确诊为ADH的病理20例存档切片,分析误诊原因。结果在20例ADH中,有13例误诊为乳腺导管原位癌(DCIS),占65%,7例误诊为普通型导管上皮增生(UDH),占35%。结论①取材不充分,观察不全面是误诊的原因之一。②ADH与低级别的DCIS极难鉴别,要严格按照权威诊断标准进行诊断。
Objective To review the misdiagnosis status of atypical hyperplasia of breast ductal epithelium (ADH), summarize the causes of misdiagnosis and improve the diagnostic level. Methods Twenty cases of pathologically confirmed ADH in the past 10 years were collected and analyzed for the causes of misdiagnosis. Results Of 20 ADH cases, 13 cases were misdiagnosed as ductal carcinoma in situ (DCIS), accounting for 65%. 7 cases were misdiagnosed as common ductal hyperplasia (UDH), accounting for 35%. Conclusion ① Insufficient harvesting and incomplete observation are one of the reasons for misdiagnosis. ②ADH and low-level DCIS very difficult to identify, in strict accordance with the authority of diagnostic criteria for diagnosis.