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放射性碘治疗甲状腺机能亢进症(以下简称甲亢)已有20多年。其缺点为继发性甲状腺机能减退症的发生率在治疗后逐年增高。本文报告自1962年起采用较小剂量放射性碘合并长程抗甲状腺药物治疗165例甲亢的结果。女病人129例(77%),男病人36例(23%)。年龄16~77岁。其中31例在应用抗甲状腺药物1~2年失效后采用本法治疗,134例由于病情较重和年龄较大而用本法治疗。 ~(131)碘剂量:根据有无甲状腺肿、甲状腺最高吸~(131)碘率及病情严重度而定。采用一次剂量者121例(73.4%),余44例(26.6%)采用数次剂量。采用一次~(131)碘治疗的121例中,2~4毫居里39例,5~6毫居里55例,6.5~10毫居里27例。抗甲状腺药物的应用:给予放射性碘48小时后服用抗甲状腺药物,第一个月每日丙基硫脲嘧啶225
Radioactive iodine treatment of hyperthyroidism (hereinafter referred to as hyperthyroidism) for more than 20 years. The disadvantage is the incidence of secondary hypothyroidism after treatment increased year by year. This article reports the results of 165 cases of hyperthyroidism treated with smaller doses of radioactive iodine and long-term anti-thyroid drugs since 1962. There were 129 female patients (77%) and 36 male patients (23%). Age 16 to 77 years old. Thirty-one of the 31 cases were treated with this method after one to two years of failure of anti-thyroid drugs and 134 cases were treated with this method due to their serious condition and age. ~ (131) iodine dose: According to the presence or absence of goiter, the maximum thyroid uptake ~ (131) iodine rate and the severity of illness may be. A single dose of 121 cases (73.4%), the remaining 44 cases (26.6%) using several doses. Of the 121 cases treated with 131I, there were 39 cases of 2 ~ 4 millicuries, 55 cases of 5 ~ 6 millicuries and 27 cases of 6.5 ~ 10 millicuries. Anti-thyroid drug application: 48 hours after giving radioactive iodine anti-thyroid drugs, the first monthly propylthiouracil 225