目的分析肺感染患者血清PCT(降钙素原)、CRP(C-反应蛋白)的变化及其联合检测的临床价值。方法回顾性分析郑煤集团总医院自2012年4月至2015年4月收治的确诊为肺部感染的60例患者的临床资料,按肺感染种类将其分为G-菌感染组、G+菌感染组与真菌感染组,选取同期来我院体检的50例正常健康者作为对照组,检测其血清PCT、CRP水平,分析两者联合检测在肺感染患者中的应用价值。结果 G-菌感染组血清CRP、PCT分别为(98.61±6.35)mg/L、(13.82±2.12)μg/L,与其他三组对比差异有统计学意义(P<0.05);PCT+CRP两项联合诊断对不同类型肺感染患者诊断准确率均达85.00%以上,高于单项检测。结论在肺感染患者的临床诊断中采用PCT联合CRP检测方案,可提高诊断准确率,且对感染类型鉴别有其较高的参考价值,值得推广。 Objective To analyze the changes of serum PCT (procalcitonin) and CRP (C-reactive protein) in patients with lung infection and the clinical value of combined detection. Methods The clinical data of 60 patients diagnosed as pulmonary infection from April 2012 to April 2015 in Zhengzhou Coal General Hospital were retrospectively analyzed. According to the types of lung infection, they were divided into G-bacteria infection group, G + bacteria In the infection group and the fungal infection group, 50 normal healthy subjects who were in our hospital during the same period were selected as the control group. The levels of PCT and CRP in serum were detected and the value of combined detection of the two in the patients with pulmonary infection was analyzed. Results The serum levels of CRP and PCT were (98.61 ± 6.35) mg / L and (13.82 ± 2.12) μg / L respectively in the group of G-bacteria infection, which were significantly different from the other three groups (P <0.05) Item diagnosis of different types of lung infections in patients with diagnostic accuracy of more than 85.00%, higher than the single test. Conclusion The combination of PCT combined with CRP in the clinical diagnosis of patients with pulmonary infection can improve the diagnostic accuracy, and it has a high reference value for the identification of infection types, which is worthy of promotion.