目的:建立分离舒必利消旋体并准确检测左舒必利片剂中主药含量的毛细管电泳法。方法:采用熔融石英毛细管柱(50μm×31 cm,有效长度为21 cm),以含2%高磺化α-环糊精的20 mmol.L-1柠檬酸钠缓冲溶液为运行缓冲液,检测波长为214 nm,分离电压为-10 kV。结果:实现了左舒必利和右舒必利的基线分离,左舒必利在0.001～0.1 mg.mL-1范围内线形关系良好,用建立的方法检测3批左舒必利片标示含量分别为97.08%,98.77%,98.78%。结论:本方法灵敏度高,简便快捷,适用于左舒必利片剂的含量测定和质量控制。 OBJECTIVE: To establish a capillary electrophoresis method for the separation of racemate from sulpiride and the accurate determination of the main drug in Zu-sulpiride tablets. Methods: A fused silica capillary column (50 μm × 31 cm, effective length of 21 cm) was used as the running buffer with 20 mmol·L-1 sodium citrate buffer solution containing 2% The wavelength is 214 nm and the separation voltage is -10 kV. RESULTS: The baseline separation of Zuvastopril and RightSepirivir was achieved. The linear relationship between Zusulpride and Zusulpride in the range of 0.001-0.1 mg.mL-1 was good. The content of the three batches of Zuvastatin tablets was 97.08% and 98.77% respectively, , 98.78%. Conclusion: The method is sensitive, simple and quick, suitable for the determination and quality control of Zusanli tablets.