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采用细胞培养、制片、G显带、核型分析等细胞遗传学方法 ,对消化道恶性肿瘤患者外周血淋巴细胞及肿瘤细胞的染色体进行了研究 ,发现患者淋巴细胞染色体多无异常 ,而肿瘤细胞的染色体均有不同程度的改变 ,经常出现的结构改变 :胃癌7q- 、食管癌 del( 1 p)、结肠癌 del( 1 7p) ,这些改变可能分别是胃癌、食管癌和结肠癌的特征性染色体结构改变
Chromosomes of peripheral blood lymphocytes and tumor cells in patients with gastrointestinal cancer were studied by means of cytogenetics, such as cell culture, production, G-banding and karyotype analysis. The results showed that there were no abnormalities in the lymphocytes of patients, Cell chromosomes have varying degrees of change, the frequent structural changes: gastric cancer 7q-, esophageal cancer del (1 p), colon cancer del (17p), these changes may be the characteristics of gastric cancer, esophageal cancer and colon cancer Sex chromosome structure changes