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目的:探索幽门螺杆菌(HP)几种临床检测方法,寻求最适宜临床推广的快速HP检测方法。方法:对本院200例因消化道症状来行胃镜检查的患者分别用快速尿素酶试验(RUT)、13C呼气试验(13C-UBT)及HP粪便抗原检测HP感染,评价其在HP检测中的敏感性、特异性及准确性。结果:此三种检测的阳性率,差异无统计学意义。通过以RUT为“金标准”比较,HpSA优于13C-UBT检测,两者有统计学意义(p<0.05)。结论:HPSA检测在对HP感染的诊断及疗效评价中具有较高的敏感性和特异性。
Objective: To explore several clinical detection methods of Helicobacter pylori (HP) and to find a rapid HP detection method that is most suitable for clinical promotion. Methods: In our hospital, 200 cases of gastroscopy due to gastrointestinal symptoms were detected by rapid urease test (RUT), 13C breath test (13C-UBT) and HP fecal antigen detection of HP infection, evaluation of HP detection Sensitivity, specificity and accuracy. Results: The positive rates of these three tests were not statistically different. HpSA was superior to 13C-UBT in terms of RUT for “gold standard”, both of which were statistically significant (p <0.05). Conclusion: HPSA test has high sensitivity and specificity in the diagnosis and evaluation of HP infection.