20世纪 70年代中期Ａｎｄｒｅａｓ等发展球囊导管后 ,开始了经导管介入治疗闭塞性冠状动脉[1,2 ] 和周围动脉[3 ] 疾病的时代 ,该技术无需血管内给药即可有效完成溶栓。尽管球囊成形术广受赞誉 ,但仍有不足之处 ,如血栓形成、夹层和痉挛等急性并发症 ;血栓过大和病变处钙化等复 In the mid-1970s Andreas and others developed balloon catheters and began an era of catheterized intervention for the treatment of diseases of the occluded coronary artery [1,2] and peripheral arteries [3], which can be effectively accomplished without intravascular administration bolt. Although balloon angioplasty is widely acclaimed, there are still deficiencies such as acute complications such as thrombosis, dissection and spasticity; excessive thrombus and calcification of the lesion