论文部分内容阅读
本文对ＨＢＶ感染后各型肝病２３８例患者血清中Ｐｒｅ－Ｓ２与ｐＨＳＡ－ｒ、ＨＢｅＡｇ标志相互关系及其临床意义进行比较。结果表明，Ｐｒｅ－Ｓ２在急性肝炎、慢活肝，ＨＢｓＡｇ无症状携带者中阳性检出率为最高，ｐＨＳＡ－ｒ、ＨＢｅＡｇ次之。亦观察到在Ｐｒｅ－Ｓ２阳性组中，ｐＨＳＡ－ｒ与ＨＢｅＡｇ阳性率相对增高（Ｐ＜０．０５，Ｐ＜０．００１），有显著差异，表明三者密切相关。Ｐｒｅ－Ｓ２更明确代表ＨＢＶ复制的感染性、传染性及对预后的估计、判断抗病毒之疗效。方法敏感、特异，适合临床广泛应用。
In this paper, the serum levels of Pre-S2, pHSA-r and HBeAg in serum of 238 patients with various liver diseases after HBV infection were compared and their clinical significance was compared. The results showed that Pre-S2 in acute hepatitis, slow-living liver, HBsAg asymptomatic carriers of the highest positive detection rate, pHSA-r, HBeAg second. The positive rates of pHSA-r and HBeAg in Pre-S2 positive group were also observed to be significantly higher (P <0.05, P <0.001), indicating a close correlation between the three. Pre-S2 more clearly represents the replication of HBV infection, infectivity and prognosis of the estimate to determine the efficacy of anti-virus. Sensitive and specific, suitable for clinical application.