大肠癌包括结肠癌和直肠癌,在世界范围都有较高的发病率,在我国恶性肿瘤中其构成比与病死率均处于第5位,且有逐年上升的趋势。治疗原则是尽可能手术切除,并配合化疗等综合治疗。但由于该肿瘤对化、放疗等表现抗拒,治疗后延长生存期的可能甚少,故近年来寻找高效、低毒的药物或其 Colorectal cancer, including colon and rectal cancer, has a high incidence in the world. In our malignant tumors, its constitutional ratio and case fatality rate are in the 5th place, and there is a trend of increasing year by year. The principle of treatment is as much as possible surgical resection, combined with chemotherapy and other comprehensive treatment. However, due to the tumor of chemotherapy, radiotherapy and other performance of resistance, prolonged survival after treatment may be very little, so in recent years to find efficient, low toxicity drugs or their