痉挛性发声障碍(SD)是一种少见的发声困难症状,其特征是声带呈一种自发性的痉挛性运动,表现为挤压、紧缩和张力过强的破裂声音,病因不明。Pool等认为是丘脑辅助运动中枢异构所致。SD可分三种亚型,即内收型、外展型、混合型。该三亚型可用嗓音的声学特征来描述。内收型最常见,注射肉毒杆菌毒素(BT)对其是一种有效的疗法。该法可使病人嗓音得到改善。若注射前嗓音越差,注射后嗓音改善越明显。疗效持续大约3个月,尽管不能永久的治愈,但在目前对内收型SD仍是最适合的。BT是一种多肽物,它能引起神经肌 Spasmodic dysphonia (SD) is a rare symptom of dysphonia characterized by a spontaneous spasmodic movement of the vocal cord, manifested as crush, tightening and excessive tensioning sounds, with unknown etiology. Pool and other that the thalamus is due to the central hub of motor activity. SD can be divided into three subtypes, namely adduction type, abduction type, mixed type. The Sanya can be described by the acoustic characteristics of the voice. Internal adduction is the most common type of injection and botulinum toxin (BT) is an effective therapy. The law can improve the patient’s voice. If the voice before the injection of the worse, the more obvious improvement after the injection of voice. The curative effect lasted about 3 months. Although it can not be permanently cured, it is still the most suitable type for internal retraction SD. BT is a polypeptide that causes neuromuscular blockade