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多发性骨髓瘤(简称MM)是一种慢性的浆细胞恶性增生症,一般发展缓慢,病程较长。诊断明确后给予化疗,多能取得缓解;但根据最近报道该症有些特殊类型,其治疗与预后都和一般典型的MM有所不同。人们将其分为预后良好和预后险恶两大类型:前者包括亚临床型和缓进型;后者包括异常蛋白血症昏迷型、急进型以及B-原免疫细胞肉瘤型。对以上各型分别简述于下。亚临床型(Smouldering MM) Kyle等报道6例亚临床型MM,其诊断依据是骨髓内浆细胞超过10％(10～17％),血
Multiple myeloma (MM) is a chronic plasma cell malignant hyperplasia, the general slow development, longer duration. Chemotherapy after diagnosis is clear, and more can be achieved; but according to the recent reports of some special types of the disease, its treatment and prognosis are generally different from the typical MM. People will be divided into two categories of good prognosis and prognosis of sinister: the former includes subclinical and slow progress; the latter includes abnormal proteinase coma type, radical type and B-cell immunosarcomatoid type. The above types were briefly described below. Sub-clinical (Smouldering MM) Kyle reported 6 cases of subclinical MM, the diagnosis is based on more than 10% of bone marrow plasma cells (10 to 17%), blood