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早期人们对兰斑的形态作了较详细的描述,并对其机能提出某些设想。自六十年代开始,一些学者应用荧光技术探讨中枢神经系中含单胺类的神经元,证明兰斑(LC)中含有儿茶酚胺,其中主要是去甲肾上腺素 norepinephrine(NE)。此后,神经生理学研究表明兰斑中含有单胺氧化酶 monoamine oxidase 在异相睡眠 Paradoxical sleep 中起着重要作用。
In the early stage, people made a detailed description of the morphology of blue spots and put forward some ideas about their functions. Since the 1960s, some scholars have used fluorescence to explore monoamine-containing neurons in the central nervous system, demonstrating that there are catecholamines in the blue spots (LC), mainly norepinephrine (NE). Since then, neurophysiological studies have shown that blue pigment contains monoamine oxidase monoamine oxidase play an important role in paradoxical sleep sleep Paradoxical sleep.