免疫反应是机体对抗入侵异性物质的生理性保护措施,同时对自身组织损坏、衰老和变异的成份也有排斥和自我调节的作用。它受遗传因素的影响,反应强弱随个体而异,若自我调节机能失调可出现抗自身组织成份的抗体,在过强的情况下可引起免疫病理现象。根据临床、动物实验和标记抗体的研究可区分为系统性自身免疫病和器官特异性自身免疫病。从临床的角度来看,系统性自身免疫病多属结缔组织病(旧称胶原病),多见于女性, Immune response is the body’s physiological protective measures against invaded foreign substances, while its own tissue damage, aging and variation of the ingredients are also exclusive and self-regulating role. It is affected by genetic factors, the intensity of the response varies with the individual, if the self-regulating dysfunction can appear anti-self-body tissue antibodies, in case of too strong can cause immune pathology. Studies based on clinical, animal experiments and labeled antibodies can be divided into systemic autoimmune diseases and organ-specific autoimmune diseases. From a clinical point of view, systemic autoimmune diseases are mostly connective tissue disease (formerly known as collagen disease), more common in women,