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目的:评估可降解止血粉应用于鼻内镜手术的有效性及舒适度。方法:前瞻性纳入2015年10月至2019年7月期间就诊于首都医科大学附属北京同仁医院的慢性鼻窦炎患者21例，患者均为双侧病变，其中男17例，女4例，年龄18~65岁，平均42岁。所有患者均接受鼻内镜手术治疗，采用同一患者左右侧鼻腔随机对照试验，若试验侧鼻腔应用可降解止血粉，则对照侧鼻腔应用可降解止血绵。患者术前CT平均评分为6.25分。术后第1、7、14、30天完成左右侧鼻腔鼻出血以及鼻塞、流涕、疼痛视觉模拟量表（VAS）评分。评估患者术后鼻内镜评分。应用SPSS 22和Graphpad prism 8.0 软件进行统计学分析。患者试验侧和对照侧之间采用配对n t检验或非参数检验。n P0.05；n t值分别为0.944、1.471、1.612、2.251，n P值均>0.05）；各鼻部症状评分差异无统计学意义（n P值均>0.05）。术后第1、7、14天，止血粉侧的材料降解评分分别为（1.33±0.21）、（0.38±0.18）、0分；低于对照侧的（2.00±0.00）、（1.95±0.22）、（1.80±0.13）分，差异有统计学意义（n P值均0.05). There was no significant difference between absorbable hemostasis powder and Nasopore side on POD 1, 7, 14 and 30 in terms of each nasal symptom VAS scores(all n P>0.05). On POD 1, 7 and 14, the packing material degeneration scores of the absorbable hemostasis powder side were significantly lower than those of the Nasopore side [(1.33±0.21)n vs(2.00±0.00),(0.38±0.18) n vs (1.95±0.22), 0 n vs (1.80±0.13), all n P<0.01]. There were significant differences between absorbable hemostasis powder and Nasopore side on POD 1, 7, 14 and 30 in terms of endoscopic scores (edema, crusting, discharges, scar, polyps and material degeneration, n t=3.07, 7.00, 6.41, 2.69, all n P<0.05).n Conclusions:The absorbable hemostasis powder and Nasopore has similar postoperative hemostasis effect. The absorbable hemostasis powder is rapidly cleared and without negative effects on mucosal wound healing 14 days postoperatively.