目前,全球约有10亿人维生素D(VD)不足或缺乏,严重危害人类的健康。既往研究更多是关注VD缺乏对骨骼健康的影响。近年来,随着医学技术的发展及对疾病的不断认识,越来越多研究认为VD缺乏不单影响骨代谢,同时也影响代谢紊乱、糖尿病、心血管疾病及肿瘤等疾病的发生[1,2]。但如何定义VD缺乏学术界尚存争议,大多数学者认为 Currently, about 1 billion people around the world have inadequate or lack of vitamin D (VD), which seriously endanger human health. Previous studies have focused more on the effects of VD deficiency on bone health. In recent years, with the development of medical technology and continuous understanding of the disease, more and more studies think that VD deficiency not only affects bone metabolism, but also affects the occurrence of metabolic disorders, diabetes, cardiovascular diseases and tumors [1,2 ]. However, how to define the lack of VD is still controversial academics, most scholars think