利血平注射液分解产物的检查

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利血平为白色或稍带黄褐色之粉末,见光后色渐变深。利血平注射液为微黄绿色带光荧的澄明液体,见光后色渐变化,从微黄绿色变为淡黄绿色、黄绿色,最后变成棕黄色,其中产生了一些什么变化?其分解产物是什么?色泽变化对质量有无影响等是个值得研究的问题。本品为治疗高血压病常用药品,为了便于广大农村及基层快速、准确地识别本品质量的好坏,本文采用薄层层析法及紫外分光光度法对利血平注射液的光氧化 Reserpine is a white or slightly yellowish brown powder, see the light after the color gradient deep. Reserpine injection for the yellowish green with fluorescent light clear liquid, see light after the gradual change from yellowish green to yellowish green, yellowish green, and finally turned brown, which produced some of what changes? What is the decomposition product? Whether the change of color has any influence on the quality is a problem worth studying. This product is commonly used drugs for the treatment of hypertension, in order to facilitate the vast rural areas and the grassroots quickly and accurately identify the quality of the product is good or bad, this paper uses TLC and UV spectrophotometry of reserpine injection of photooxidation
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