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采用荧光偏振免疫法对１９０例眼用丙戊酸的癫痫患者进行丙戊酸血浓度监测，分析总结了４１７份血药浓度与剂量及疗效的关系，达到丙戊酸治疗血浓度范围（５０～１００μｇ／ｍｌ）但未有效控制症状的有３４例次，占１５％；不在治疗血药浓度范围内而症状控制良好的有４３例，占２１％。结果表明，丙戊酸血浓度监测对抗癫痫药物合理应用有重要指导作用，但个体化给药还必须综合考虑各方面的因素。
Fluorescence polarization immunoassay was used to monitor the blood concentration of valproic acid in 190 epileptic patients with ocular valproic acid. The relationship between blood concentration and dose and efficacy was summarized and reached the range of 50 ~ 100μg / ml) but did not effectively control the symptoms of 34 cases, accounting for 15%; not in the treatment of plasma concentration within the well-controlled symptoms of 43 cases, accounting for 21%. The results showed that the monitoring of valproic acid concentration of antiepileptic drugs to monitor the rational use of an important guiding role, but the individual administration must also consider all aspects of factors.