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目的观察克罗米芬联合人绒毛膜促性腺激素治疗不孕不育的临床效果。方法选取医院收治的多囊卵巢综合征引发的不孕不育患者80例,随机分为观察组和对照组,每组40例。观察组采用克罗米芬联合人绒毛膜促性腺激素治疗,对照组采用克罗米芬治疗,观察2组患者的临床疗效,睾酮(T)、黄体生成素(LH)、促卵泡激素(FSH)及空腹胰岛素(FINS)各项指标。结果观察组总有效率为97.5%,高于对照组的77.5%(P<0.05);治疗后,观察组睾酮(T)、黄体生成素(LH)、促卵泡激素(FSH)和空腹胰岛素(FINS)各项指标优于对照组,差异均有统计学意义(P<0.05)。结论由于多囊卵巢综合征导致的不孕不育患者采取克罗米芬联合人绒毛膜促性腺激素治疗具有很好的临床疗效,临床症状得到明显改善。
Objective To observe the clinical effect of clomiphene in combination with human chorionic gonadotropin in the treatment of infertility. Methods 80 cases of infertility caused by polycystic ovary syndrome in hospital were randomly divided into observation group and control group, 40 cases in each group. The observation group was treated with clomiphene combined with human chorionic gonadotropin, and the control group was treated with clomiphene. The clinical effects, testosterone (T), luteinizing hormone (LH), follicle stimulating hormone (FSH) and fasting insulin (FINS) indicators. Results The total effective rate in observation group was 97.5%, which was higher than that in control group (P <0.05). After treatment, the levels of testosterone, LH, FSH and fasting insulin FINS) than the control group, the differences were statistically significant (P <0.05). Conclusions Clomiphene combined with human chorionic gonadotropin therapy in patients with infertility caused by polycystic ovary syndrome has good clinical efficacy and clinical symptoms have been significantly improved.