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目的探讨D-二聚体定量检测对急性肺栓塞与急性心肌梗死鉴别诊断种临床价值。方法选取28例急性肺栓塞患者与32例急性心肌梗死患者,采用Sysmex CA-1500全自动凝血分析仪检测发病前、发病后血浆D-二聚体含量并进行比较。结果急性肺栓塞患者血浆D-二聚体水平显著高于急性心肌梗死患者(P<0.01),两者与正常对照组相比较差异均有统计学意义(P<0.05)。结论急性肺栓塞患者血浆D-二聚体水平明显高于急性心肌梗死患者,能够有效区分临床表现不典型急性肺栓塞与急性心肌梗死患者,D-二聚体定量检测在两者鉴别中具有重要临床参考价值。
Objective To investigate the clinical value of quantitative detection of D-dimer in the differential diagnosis of acute pulmonary embolism and acute myocardial infarction. Methods Twenty-eight patients with acute pulmonary embolism and 32 patients with acute myocardial infarction were enrolled in this study. The plasma D-dimer levels before and after onset were detected by Sysmex CA-1500 automatic coagulation analyzer and compared. Results The plasma levels of D-dimer in patients with acute pulmonary embolism were significantly higher than those in patients with acute myocardial infarction (P <0.01). There was significant difference between the two groups (P <0.05). Conclusion The plasma D-dimer levels in patients with acute pulmonary embolism were significantly higher than those in patients with acute myocardial infarction and could effectively distinguish patients with atypical acute pulmonary embolism and acute myocardial infarction. The quantitative detection of D-dimer is important in the differential diagnosis Clinical reference value.